FoldX plugin for YASARA

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Welcome to the homepage of the FoldX plugin for YASARA

FoldX tools menu in YASARA

The FoldX plugin for YASARA is a software package to access and run FoldX commands in YASARA.

FoldX is a molecular modeling and protein design software program that calculates energy differences that come close to experimental values. FoldX can minimize a PDB structure, mutate one or more residues to new residues, do protein stability analysis, protein-protein interaction energy analysis and much more. FoldX is widely used to predict the effect of mutations on the stability of a protein or to predict the effect on protein-protein binding.

YASARA is a molecular-graphics, -modeling and -simulation program that finally makes it really easy to answer your biological questions. The 3D graphics and intuitive interface make it a very user-friendly protein and nucleic acid analysis package. It is also easily extendable by means of plugins.

FoldX is normally run from the command line without graphics. By installing the FoldX plugin for YASARA, you can access the most important FoldX tools at the touch of a button in the 3D graphical YASARA interface. You directly see the results of your FoldX protein analysis on screen.

FoldX, YASARA and the FoldX plugin for YASARA are all available for Linux, MacOSX and Windows.

This website is a guide through the installation and usage of the FoldX plugin for YASARA.

Have fun!

Attention: Since FoldX 4 has been released you can no longer download the plugin from this site. FoldX 4 and the additional YASARA plugin can only be downloaded from This website will remain alive so you can still browse the guide of the most important FoldX tools in YASARA including lots of screenshots and documentation.

Topics in this guide



YASARA version information

The plugin only works properly from YASARA version 12.2.20 and higher. Upgrading to the latest YASARA is strongly recommended.


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