FoldX plugin for YASARA

Welcome to the homepage of the FoldX plugin for YASARA

FoldX tools menu in YASARA

The FoldX plugin for YASARA is a software package to access and run FoldX commands in YASARA.

FoldX is a molecular modeling and protein design software program that calculates energy differences that come close to experimental values. FoldX can minimize a PDB structure, mutate one or more residues to new residues, do protein stability analysis, protein-protein interaction energy analysis and much more. FoldX is widely used to predict the effect of mutations on the stability of a protein or to predict the effect on protein-protein binding.

YASARA is a molecular-graphics, -modeling and -simulation program that finally makes it really easy to answer your biological questions. The 3D graphics and intuitive interface make it a very user-friendly protein and nucleic acid analysis package. It is also easily extendable by means of plugins.

FoldX is normally run from the command line without graphics. By installing the FoldX plugin for YASARA, you can access the most important FoldX tools at the touch of a button in the 3D graphical YASARA interface. You directly see the results of your FoldX protein analysis on screen.

FoldX, YASARA and the FoldX plugin for YASARA are all available for Linux, MacOSX and Windows.

This website is a guide through the installation and usage of the FoldX plugin for YASARA.

Have fun!

News

We are very pleased to announce that the FoldX plugin for YASARA has been published in Bioinformatics!
Citation details are right over here.

Topics in this guide

• Installation and first use
• Guide of FoldX tools in YASARA
• Tutorial with real-world examples
• Troubleshooting
• Changelog

Miscellaneous

• Download PDF manual
• Request a new feature
• Citing
• Contact and support
• Special thanks
• More YASARA plugins from our group

Download

• FoldX plugin for YASARA version 1.4.21

FoldX version information

FoldX 3 Beta 5 is required for the plugin to work. The Beta 4 has expired and doesn't work anymore. Get the new version from http://foldx.crg.es.

YASARA version information

The plugin only works properly from YASARA version 10.11.22 and higher. Upgrading to the latest YASARA is strongly recommended.

Links

• foldx.crg.es FoldX website
• www.yasara.org YASARA website
• switch.vub.ac.be Switch Laboratory
• www.python.org Python website